Cefuroxime disc susceptibility test criteria for Streptococcus penumoniae

Streptococcus penumoniae meningitis. Clinical and experimental studies.

Predicting susceptibility of Streptococcus pneumoniae to ceftriaxone and cefotaxime by cefuroxime and ceftizoxime disk diffusion testing.

In this study, disk diffusion testing with ceftizoxime and cefuroxime was evaluated for use in predicting the susceptibility of Streptococcus pneumoniae to ceftriaxone and cefotaxime. Of the 194 isolates included in this study, 138 were susceptible, 34 were intermediate, and 22 were resistant to cefotaxime by MIC testing; 138 isolates were susceptible, 35 were intermediate, and 21 were resistan...

Interpretative criteria and quality control parameters for telithromycin disc diffusion susceptibility tests.

In vitro studies were carried out with 4175 Gram-positive clinical isolates, comparing telithromycin broth microdilution MICs with disc diffusion zone diameters. Provisional interpretive criteria for testing staphylococci were > or =23 mm for susceptible and < or =19 mm for resistant. Because pneumococci and other streptococci require increased CO(2), the corresponding zone sizes are 3 mm small...

Disc antibiogram test with graded plate method

Abstract Background and objectives: Halo interference around antibiogram disc is one of the problems seen in Agar media. This study aimed at applying graded plate method to reduce this problem. Material and Methods: Forty-eight millimeter plates, before putting disc, were graded and the location of discs was determined. Instead of full disc, we used half-disc and then compared the haloe interfe...

Unreliability of disc diffusion test for screening for reduced penicillin susceptibility in Neisseria meningitidis.

The 2-U penicillin and microgram oxacillin discs proposed for screening meningococci for susceptibility to penicillin were evaluated by using MICs measured by the E test. The discs yielded unacceptably high frequencies of misclassification of susceptibility category and should be abandoned in favor of MIC estimations. An agreed breakpoint for reduced penicillin susceptibility in meningococci is...